Development of machine learning models for the prediction of the skin sensitization potential of cosmetic compounds

Background To enhance the accuracy of allergen detection in cosmetic compounds, we developed a co-culture system that combines HaCaT keratinocytes (transfected with a luciferase plasmid driven by the AKR1C2 promoter) and THP-1 cells for machine learning applications. Methods Following chemical expos...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Wu Qiao, Tong Xie, Jing Lu, Tinghan Jia
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: PeerJ Inc. 2024-12-01
Цуврал:PeerJ
Нөхцлүүд:
Онлайн хандалт:https://peerj.com/articles/18672.pdf