Development of machine learning models for the prediction of the skin sensitization potential of cosmetic compounds

Development of machine learning models for the prediction of the skin sensitization potential of cosmetic compounds

Background To enhance the accuracy of allergen detection in cosmetic compounds, we developed a co-culture system that combines HaCaT keratinocytes (transfected with a luciferase plasmid driven by the AKR1C2 promoter) and THP-1 cells for machine learning applications. Methods Following chemical expos...

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Bibliografiska uppgifter
Huvudupphovsmän: Wu Qiao, Tong Xie, Jing Lu, Tinghan Jia
Materialtyp: Artikel
Språk:English
Publicerad: PeerJ Inc. 2024-12-01
Serie:PeerJ
Ämnen:
Machine learning
Skin sensitization
Co-culture
THP-1
RNA-Seq
Länkar:https://peerj.com/articles/18672.pdf

Internet

https://peerj.com/articles/18672.pdf

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