Development of machine learning models for the prediction of the skin sensitization potential of cosmetic compounds

Development of machine learning models for the prediction of the skin sensitization potential of cosmetic compounds

Background To enhance the accuracy of allergen detection in cosmetic compounds, we developed a co-culture system that combines HaCaT keratinocytes (transfected with a luciferase plasmid driven by the AKR1C2 promoter) and THP-1 cells for machine learning applications. Methods Following chemical expos...

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Detaylı Bibliyografya
Asıl Yazarlar: Wu Qiao, Tong Xie, Jing Lu, Tinghan Jia
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: PeerJ Inc. 2024-12-01
Seri Bilgileri:PeerJ
Konular:
Machine learning
Skin sensitization
Co-culture
THP-1
RNA-Seq
Online Erişim:https://peerj.com/articles/18672.pdf

Internet

https://peerj.com/articles/18672.pdf

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