PRMT1‐mediated arginine methylation promotes YAP activation and hepatocellular carcinoma proliferation

The activity of Hippo signaling is commonly dysregulated in various human malignancies, including hepatocellular carcinoma (HCC). YAP, the key effector of Hippo pathway, is regulated through several posttranslational modifications. However, the mechanism by which YAP is regulated by arginine methyla...

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Bibliographic Details
Main Authors: Jian Yu, Beibei Yu, Zushun Peng, Jianfeng Zhang, Juhui Sun, Bo Yang, Liushiyang Xu, De Luo
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.13909