Curcumin-loaded graphene oxide quantum dots enhance otoprotective effects via blocking cuproptosis

Curcumin-loaded graphene oxide quantum dots enhance otoprotective effects via blocking cuproptosis

Background: Cisplatin (CIS) is widely used to treat various cancers but can cause ototoxicity and sensory hair cell loss in the inner ear. Copper induces an excessive production of reactive oxygen species (ROS) in hair cells, leading to the development of various antioxidants.Methods and results: Th...

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Bibliographic Details
Main Authors: An Hu, Jian-Wei Zhang, Li-Yun Yang, Pei-Pei Qiao, Dan Lu, Ya-Feng Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
graphene oxide quantum dots
curcumin
ototoxicity
reactive oxygen species
cuproptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1183197/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1183197/full

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