Ticagrelor Prevents Endothelial Cell Apoptosis through the Adenosine Signalling Pathway in the Early Stages of Hypoxia

Ticagrelor Prevents Endothelial Cell Apoptosis through the Adenosine Signalling Pathway in the Early Stages of Hypoxia

Background: Several studies have reported the beneficial effects of anti-platelet drugs in cardioprotection against ischaemia–reperfusion injuries. To date, no studies have focused on the indirect cytoprotective effects of ticagrelor via adenosine receptor on the endothelium. Method: By evaluating c...

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Bibliographic Details
Main Authors: Catherine Feliu, Hélène Peyret, Sylvie Brassart-Pasco, Floriane Oszust, Gaël Poitevin, Philippe Nguyen, Hervé Millart, Zoubir Djerada
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Biomolecules
Subjects:
ticagrelor
cytoprotective effect
endothelium
extracellular adenosine
adenosine receptors
Online Access:https://www.mdpi.com/2218-273X/10/5/740

Internet

https://www.mdpi.com/2218-273X/10/5/740

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