Fcmr regulates mononuclear phagocyte control of anti-tumor immunity

Fcmr regulates mononuclear phagocyte control of anti-tumor immunity

Myeloid cells modulate the immune response within the tumour microenvironment, but the underlying mechanisms remain largely unknown. Here, the authors show that Fcmr – the putative receptor for soluble IgM – is a potent negative regulator of anti-tumour immunity.

Bibliographic Details
Main Authors: Shawn P. Kubli, Larsen Vornholz, Gordon Duncan, Wenjing Zhou, Parameswaran Ramachandran, Jerome Fortin, Maureen Cox, SeongJun Han, Robert Nechanitzky, Duygu Nechanitzky, Bryan E. Snow, Lisa Jones, Wanda Y. Li, Jillian Haight, Andrew Wakeham, Mark R. Bray, Tak W. Mak
Format: Article
Language:English
Published: Nature Portfolio 2019-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10619-w

Internet

https://doi.org/10.1038/s41467-019-10619-w

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