Motif-Aware PRALINE: Improving the alignment of motif regions.

Protein or DNA motifs are sequence regions which possess biological importance. These regions are often highly conserved among homologous sequences. The generation of multiple sequence alignments (MSAs) with a correct alignment of the conserved sequence motifs is still difficult to achieve, due to t...

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Bibliographic Details
Main Authors: Maurits Dijkstra, Punto Bawono, Sanne Abeln, K Anton Feenstra, Wan Fokkink, Jaap Heringa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC6233922?pdf=render