Inflammation and cytomegalovirus viremia during pregnancy drive sex-differentiated differences in mortality and immune development in HIV-exposed infants

Inflammation and cytomegalovirus viremia during pregnancy drive sex-differentiated differences in mortality and immune development in HIV-exposed infants

Abstract Children who are HIV-exposed but uninfected have increased infectious mortality compared to HIV-unexposed children, raising the possibility of immune abnormalities following exposure to maternal viraemia, immune dysfunction, and co-infections during pregnancy. In a secondary analysis of the...

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Bibliographic Details
Main Authors: Ceri Evans, Kuda Mutasa, Sandra Rukobo, Margaret Govha, Patience Mushayanembwa, Bernard Chasekwa, Florence D. Majo, Naume V. Tavengwa, Jonathan Broad, Christie Noble, Ethan K. Gough, Paul Kelly, Claire D. Bourke, Jean H. Humphrey, Robert Ntozini, Andrew J. Prendergast
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-44166-2

Internet

https://doi.org/10.1038/s41467-023-44166-2

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