The Anti-Dengue Virus Peptide DV2 Inhibits Zika Virus Both In Vitro and In Vivo

The Anti-Dengue Virus Peptide DV2 Inhibits Zika Virus Both In Vitro and In Vivo

The C-terminal portion of the E protein, known as stem, is conserved among flaviviruses and is an important target to peptide-based antiviral strategies. Since the dengue (DENV) and Zika (ZIKV) viruses share sequences in the stem region, in this study we evaluated the cross-inhibition of ZIKV by the...

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Bibliographic Details
Main Authors: Maria Fernanda de Castro-Amarante, Samuel Santos Pereira, Lennon Ramos Pereira, Lucas Souza Santos, Alexia Adrianne Venceslau-Carvalho, Eduardo Gimenes Martins, Andrea Balan, Luís Carlos de Souza Ferreira
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Viruses
Subjects:
Zika virus
peptide
antiviral
DV2 peptide
dengue virus
flavivirus
Online Access:https://www.mdpi.com/1999-4915/15/4/839

Internet

https://www.mdpi.com/1999-4915/15/4/839

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