Glutamatergic Neurotransmission Controls the Functional Lateralization of the mPFC in the Modulation of Anxiety Induced by Social Defeat Stress in Male Mice

Glutamatergic Neurotransmission Controls the Functional Lateralization of the mPFC in the Modulation of Anxiety Induced by Social Defeat Stress in Male Mice

The rodent medial prefrontal cortex (mPFC) is anatomically divided into cingulate (Cg1), prelimbic (PrL), and infralimbic (IL) subareas. The left and right mPFC (L and RmPFC) process emotional responses induced by stress-related stimuli, and LmPFC and RmPFC inhibition elicit anxiogenesis and anxioly...

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Bibliographic Details
Main Authors: Nathália Santos-Costa, Daniela Baptista-de-Souza, Lucas Canto-de-Souza, Vinícius Fresca da Costa, Ricardo Luiz Nunes-de-Souza
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
mPFC
anxiety
ΔFosB
CaMKII
glutamatergic neurotransmission
chronic social defeat stress
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2021.695735/full

Internet

https://www.frontiersin.org/articles/10.3389/fnbeh.2021.695735/full

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