The Effects of Synthetic SREBP-1 and PPAR-γ Decoy Oligodeoxynucleotide on Acne-like Disease In Vivo and In Vitro via Lipogenic Regulation

The Effects of Synthetic SREBP-1 and PPAR-γ Decoy Oligodeoxynucleotide on Acne-like Disease In Vivo and In Vitro via Lipogenic Regulation

Acne vulgaris has a pathogenesis that involves increased sebum production and perifollicular inflammation. Sterol regulatory element-binding protein-1 (SREBP-1) and peroxisome proliferator activated receptor-γ (PPAR-γ) are transcription factors that regulate numerous genes involved in lipid biosynth...

Full description

Bibliographic Details
Main Authors: Hyemin Gu, Hyun-Jin An, Mi-Gyeong Gwon, Seongjae Bae, Christos C. Zouboulis, Kwan-Kyu Park
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomolecules
Subjects:
decoy oligodeoxynucleotide
lipogenic regulation
peroxisome proliferator activated receptor-γ
sterol regulatory element-binding protein-1
Online Access:https://www.mdpi.com/2218-273X/12/12/1858

Internet

https://www.mdpi.com/2218-273X/12/12/1858

Similar Items