A dhfr-ts- Leishmania major Knockout Mutant Cross-protects against Leishmania amazonensis

A dhfr-ts- Leishmania major Knockout Mutant Cross-protects against Leishmania amazonensis

E10-5A3 is a dhfr-ts- Leishmania major double knockout auxotrophic shown previously to induce substantial protection against virulent L. major infection in both genetically susceptible and resistant mice. We investigated the capacity of dhfr-ts- to protect against heterologous infection by L. amazon...

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Bibliographic Details
Main Authors: PST Veras, CI Brodskyn, FMP Balestieri, LAR de Freitas, APS Ramos, ARP Queiroz, A Barral, SM Beverley, M Barral-Netto
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 1999-07-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
auxotrophic Leishmania major
Leishmania amazonensis
immunization
cross
protection
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000400011

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000400011

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