Continuous and low-energy <sup>125</sup>I seed irradiation changes DNA methyltransferases expression patterns and inhibits pancreatic cancer tumor growth

Continuous and low-energy <sup>125</sup>I seed irradiation changes DNA methyltransferases expression patterns and inhibits pancreatic cancer tumor growth

<p>Abstract</p> <p>Background</p> <p>Iodine 125 (<sup>125</sup>I) seed irradiation is an effective treatment for unresectable pancreatic cancers. However, the radiobiological mechanisms underlying brachytherapy remain unclear. Therefore, we investigated the...

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Bibliographic Details
Main Authors: Gong Yan-fang, Wang Luo-wei, Pan Xue, Wu Hong-yu, Lu Zheng, Liu Yan, Si Pei-ren, Jin Zhen-dong, Ma Jian-xia, Gao Jun, Zhao-shen Li
Format: Article
Language:English
Published: BMC 2011-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
<sup>125</sup>I Seed Irradiation
Pancreatic Cancer
DNA methyltransferases
DNA hypomethylation
Apoptosis
Online Access:http://www.jeccr.com/content/30/1/35

Internet

http://www.jeccr.com/content/30/1/35

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