Molded Round Window Niche Implant as a Dexamethasone Delivery System in a Cochlear Implant-Trauma Animal Model

Molded Round Window Niche Implant as a Dexamethasone Delivery System in a Cochlear Implant-Trauma Animal Model

Background: Preserving residual hearing after cochlear implant (CI) surgery remains a crucial challenge. The application of dexamethasone (DEX) has been proven to positively affect residual hearing. To deliver DEX in a localized and controlled way, a round window niche implant (RNI), allowing drug d...

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Bibliographic Details
Main Authors: Chunjiang Wei, Ziwen Gao, Robert Mau, Thomas Eickner, Gabor Jüttner, Nicklas Fiedler, Hermann Seitz, Thomas Lenarz, Verena Scheper
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Pharmaceutics
Subjects:
local inner ear drug therapy
round window niche implant
cochlear implant surgery
dexamethasone
guinea pig
local pharmacotherapy
Online Access:https://www.mdpi.com/1999-4923/16/9/1236

Internet

https://www.mdpi.com/1999-4923/16/9/1236

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