Mucoadhesive Hybrid System of Silk Fibroin Nanoparticles and Thermosensitive In Situ Hydrogel for Amphotericin B Delivery: A Potential Option for Fungal Keratitis Treatment

Mucoadhesive Hybrid System of Silk Fibroin Nanoparticles and Thermosensitive In Situ Hydrogel for Amphotericin B Delivery: A Potential Option for Fungal Keratitis Treatment

The purpose of this work was to investigate the feasibility of a novel ophthalmic formulation of amphotericin B-encapsulated silk fibroin nanoparticles incorporated in situ hydrogel (AmB-FNPs ISG) for fungal keratitis (FK) treatment. AmB-FNPs ISG composites were successfully developed and have shown...

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Bibliographic Details
Main Authors: Pratthana Chomchalao, Nuttawut Saelim, Supaporn Lamlertthon, Premnapa Sisopa, Waree Tiyaboonchai
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Polymers
Subjects:
mucoadhesive eye drops
amphotericin B
silk fibroin nanoparticles
composite formulations
ocular drug delivery
Online Access:https://www.mdpi.com/2073-4360/16/1/148

Internet

https://www.mdpi.com/2073-4360/16/1/148

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