Antigen Gene Transfer to Human Plasmacytoid Dendritic Cells Using Recombinant Adenovirus and Vaccinia Virus Vectors

Recombinant adenoviruses (RAd) and recombinant vaccinia viruses (RVV) expressing tumour-associated antigens (TAA) are used as anti-tumour vaccines. It is important that these vaccines deliver the TAA to dendritic cells (DC) for the induction of a strong immune response. Infection of myeloid DC (MDC)...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Hetty J. Bontkes, Janneke J. Ruizendaal, Marco W. J. Schreurs, Duco Kramer, Chris J. L. M. Meijer, Erik Hooijberg
Format: Artikel
Sprache:English
Veröffentlicht: Wiley 2005-01-01
Schriftenreihe:Cellular Oncology
Online Zugang:http://dx.doi.org/10.1155/2005/753549