Co-Occurrence of Germline Genomic Variants and Copy Number Variations in Hereditary Breast and Colorectal Cancer Patients

Co-Occurrence of Germline Genomic Variants and Copy Number Variations in Hereditary Breast and Colorectal Cancer Patients

Hereditary Breast and Ovarian Cancer (HBOC) syndrome is an autosomal dominant disease associated with a high risk of developing breast, ovarian, and other malignancies. Lynch syndrome is caused by mutations in mismatch repair genes predisposing to colorectal and endometrial cancers, among others. A...

Full description

Bibliographic Details
Main Authors: Luiza Côrtes, Tatiane Ramos Basso, Rolando André Rios Villacis, Jeferson dos Santos Souza, Mads Malik Aagaard Jørgensen, Maria Isabel Achatz, Silvia Regina Rogatto
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Genes
Subjects:
hereditary breast and ovarian cancer syndrome
colorectal cancer
whole exome sequencing
<i>PMS2</i>
copy number alteration
Online Access:https://www.mdpi.com/2073-4425/14/8/1580

Internet

https://www.mdpi.com/2073-4425/14/8/1580

Similar Items