Hypoxia induces polycystin-1 expression in the renal epithelium

Mutations in polycystin-1 which is encoded by the PKD1 gene are the main causes for the development of autosomal dominant polycystic kidney disease. However, only little is known about the physiological function of polycystin-1 and even less about the regulation of its expression. Here, we show that...

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Bibliographic Details
Main Authors: Steffen Grampp, Andre Kraus, Kathrin Skoczynski, Mario Schiffer, René Krüger, Stephanie Naas, Johannes Schödel, Bjoern Buchholz
Format: Article
Language:English
Published: The Royal Society 2023-05-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.220992