Subcellular localization of X-linked inhibitor of apoptosis protein (XIAP) in cancer: Does that matter?

X-linked inhibitor of apoptosis protein (XIAP) finely tunes the balance between survival and death to control homeostasis. XIAP is found aberrantly expressed in cancer, which has been shown to promote resistance to therapy-induced apoptosis and confer poor outcome. Despite its predominant cytoplasmi...

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Bibliographic Details
Main Authors: BS Mendonça, CA Ferreira, RC Maia, G Nestal de Moraes
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:BBA Advances
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667160322000114