Promoter Hypermethylation Analysis of Host Genes in Cervical Cancer Patients With and Without Human Immunodeficiency Virus in Botswana

Promoter Hypermethylation Analysis of Host Genes in Cervical Cancer Patients With and Without Human Immunodeficiency Virus in Botswana

Background: Epidemics of human immunodeficiency virus (HIV) and cervical cancer are interconnected. DNA hypermethylation of host genes' promoter in cervical lesions has also been recognized as a contributor to cervical cancer progression.Methods: For this purpose we analyzed promoter methylatio...

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Bibliographic Details
Main Authors: Leabaneng Tawe, Surbhi Grover, Nicola Zetola, Erle S. Robertson, Simani Gaseitsiwe, Sikhulile Moyo, Ishmael Kasvosve, Giacomo M. Paganotti, Mohan Narasimhamurthy
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
Botswana
invasive cervical cancer
human immunodeficiency virus
DNA methylation
tumor supressor gene
human papillomavirus
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.560296/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.560296/full

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