Cell surface receptors for signal transduction and ligand transport: a design principles study.

Receptors constitute the interface of cells to their external environment. These molecules bind specific ligands involved in multiple processes, such as signal transduction and nutrient transport. Although a variety of cell surface receptors undergo endocytosis, the systems-level design principles t...

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Bibliographic Details
Main Authors: Harish Shankaran, Haluk Resat, H Steven Wiley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1885276?pdf=render