No influence of the polymorphisms <it>CYP2C19 </it>and <it>CYP2D6 </it>on the efficacy of cyclophosphamide, thalidomide, and bortezomib in patients with Multiple Myeloma

<p>Abstract</p> <p>Background</p> <p>The response to treatment varies among patients with multiple myeloma and markers for prediction of treatment outcome are highly needed. Bioactivation of cyclophosphamide and thalidomide, and biodegradation of bortezomib, is dependen...

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Bibliographic Details
Main Authors: Vogel Ulla, Gregersen Henrik, Gimsing Peter, Abildgaard Niels, Andersen Niels F, Klausen Tobias W, Søeby Karen, Vangsted Annette J, Werge Thomas, Rasmussen Henrik B
Format: Article
Language:English
Published: BMC 2010-08-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/404