Maternal HIV-1 Env Vaccination for Systemic and Breast Milk Immunity To Prevent Oral SHIV Acquisition in Infant Macaques

Maternal HIV-1 Env Vaccination for Systemic and Breast Milk Immunity To Prevent Oral SHIV Acquisition in Infant Macaques

ABSTRACT Mother-to-child transmission (MTCT) of human immunodeficiency virus type 1 (HIV-1) contributes to an estimated 150,000 new infections annually. Maternal vaccination has proven safe and effective at mitigating the impact of other neonatal pathogens and is one avenue toward generating the pot...

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Bibliographic Details
Main Authors: Joshua A. Eudailey, Maria L. Dennis, Morgan E. Parker, Bonnie L. Phillips, Tori N. Huffman, Camden P. Bay, Michael G. Hudgens, Roger W. Wiseman, Justin J. Pollara, Genevieve G. Fouda, Guido Ferrari, David J. Pickup, Pamela A. Kozlowski, Koen K. A. Van Rompay, Kristina De Paris, Sallie R. Permar
Format: Article
Language:English
Published: American Society for Microbiology 2018-02-01
Series:mSphere
Subjects:
HIV-1
breast milk
maternal vaccination
oral challenge
placental transfer
transmission
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00505-17

Internet

https://journals.asm.org/doi/10.1128/mSphere.00505-17

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