Various Subtypes of EGFR Mutations in Patients With NSCLC Define Genetic, Immunologic Diversity and Possess Different Prognostic Biomarkers

Various Subtypes of EGFR Mutations in Patients With NSCLC Define Genetic, Immunologic Diversity and Possess Different Prognostic Biomarkers

Based on data analysis of 9649 Chinese primary NSCLC patients, we calculated the exact proportion of EGFR subtypes in NSCLC and evaluated the TMB level, PD-L1 expression level and tumor immune microenvironment among different EGFR mutation subtypes. Postoperative follow-up data for 98 patients were...

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Bibliographic Details
Main Authors: Youming Lei, Kun Wang, Yinqiang Liu, Xuming Wang, Xudong Xiang, Xiangu Ning, Wanbao Ding, Jin Duan, Dingbiao Li, Wei Zhao, Yi Li, Fujun Zhang, Xiaoyu Luo, Yunfei Shi, Ying Wang, Depei Huang, Yuezong Bai, Hushan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
NSCLC
EGFR - epidermal growth factor receptor
immune microenviroment
prognosis
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.811601/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.811601/full

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