Synthesis of Polyanionic C5-Modified 2′-Deoxyuridine and 2′-Deoxycytidine-5′-Triphosphates and Their Properties as Substrates for DNA Polymerases

Synthesis of Polyanionic C5-Modified 2′-Deoxyuridine and 2′-Deoxycytidine-5′-Triphosphates and Their Properties as Substrates for DNA Polymerases

Modified 2′-deoxyribonucleotide triphosphates (dNTPs) have widespread applications in both existing and emerging biomolecular technologies. For such applications it is an essential requirement that the modified dNTPs be substrates for DNA polymerases. To date very few examples of C5-modified dNTPs b...

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Hlavní autoři: Claire Dutson, Esther Allen, Mark J. Thompson, Joseph H. Hedley, Heather E. Murton, David M. Williams
Médium: Článek
Jazyk:English
Vydáno: MDPI AG 2021-04-01
Edice:Molecules
Témata:
C5-modified dNTPs
polyanionic reporter group
DNA polymerases
On-line přístup:https://www.mdpi.com/1420-3049/26/8/2250

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https://www.mdpi.com/1420-3049/26/8/2250

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