Mechanisms of RON-mediated epithelial-mesenchymal transition in MDCK cells through the MAPK pathway

The epithelial-mesenchymal transition (EMT) is involved in neoplastic metastasis, and the RON protein may be involved. In the present study, we determined the role and the mechanisms of action of RON in EMT in Madin-Darby canine kidney (MDCK) cells by Western blot and cell migration analysis. Activa...

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Bibliographic Details
Main Authors: Xu Xiangming, Qian Yun, Zhang Guoliang, Lin Jianjiang, Teng Lisong
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2011-07-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000700004&lng=en&tlng=en