Plant-derived bisbenzylisoquinoline alkaloid tetrandrine prevents human podocyte injury by regulating the miR-150-5p/NPHS1 axis

Podocytes have become a crucial target for kidney disease. Tetrandrine (TET), the main active component of a Chinese medicine formula Fangji Huangqi Tang, has shown a positive effect on various renal diseases. We aimed to investigate the effect and mechanism of TET on podocytes. The targeting relati...

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Bibliographic Details
Main Authors: Sun Yue, Yuan Chenyi, Yu Jin, Zhu Caifeng, Wei Xia, Yin Jiazhen
Format: Article
Language:English
Published: De Gruyter 2022-12-01
Series:Open Chemistry
Subjects:
Online Access:https://doi.org/10.1515/chem-2022-0259