AMEERA-4: a randomized, preoperative window-of-opportunity study of amcenestrant versus letrozole in early breast cancer

AMEERA-4: a randomized, preoperative window-of-opportunity study of amcenestrant versus letrozole in early breast cancer

Abstract Background Window-of-opportunity (WOO) studies provide insights into the clinical activity of new drugs in breast cancer. Methods AMEERA-4 (NCT04191382) was a WOO study undertaken to compare the pharmacodynamic effects of amcenestrant, a selective estrogen receptor degrader, with those of l...

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Bibliographic Details
Main Authors: Mario Campone, François-Clément Bidard, Patrick Neven, Lei Wang, Bin Ling, Yvonne Dong, Gautier Paux, Christina Herold, Ugo De Giorgi
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Breast Cancer Research
Subjects:
Amcenestrant
Early breast cancer
Ki67
Postmenopausal
Window-of-opportunity study
Online Access:https://doi.org/10.1186/s13058-023-01740-2

Internet

https://doi.org/10.1186/s13058-023-01740-2

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