<i>THBS1</i>-Mediated Degradation of Collagen via the PI3K/AKT Pathway Facilitates the Metastasis and Poor Prognosis of OSCC

<i>THBS1</i>-Mediated Degradation of Collagen via the PI3K/AKT Pathway Facilitates the Metastasis and Poor Prognosis of OSCC

Oral squamous cell carcinoma (OSCC) is a prevalent form of malignant tumor, characterized by a persistently high incidence and mortality rate. The extracellular matrix (ECM) plays a crucial role in the initiation, progression, and diverse biological behaviors of OSCC, facilitated by mechanisms such...

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Bibliographic Details
Main Authors: Zhihao Wen, Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Jing Mao, Qilin Li, Shiqiang Gong
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
oral squamous cell carcinoma (OSCC)
extracellular matrix (ECM)
collagen degradation
prognosis
immunotherapy
Online Access:https://www.mdpi.com/1422-0067/24/17/13312

Internet

https://www.mdpi.com/1422-0067/24/17/13312

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