Purification and characterization of soluble recombinant Crimean-Congo hemorrhagic fever virus glycoprotein Gc expressed in mammalian 293F cells

Abstract Background Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne zoonotic disease that presents with severe hemorrhagic manifestations and is associated with significant fatality rates. The causative agent, Crimean-Congo Hemorrhagic Fever Virus (CCHFV), is a high-priority pathogen identifi...

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Bibliographic Details
Main Authors: Nigel Aminake Makoah, Matefo Millicent Litabe, Fredy Brice Nemg Simo, Katlego Keith Maboho, Felicity Jane Burt
Format: Article
Language:English
Published: BMC 2024-08-01
Series:BMC Biotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12896-024-00885-y