Loss of Female Sex Hormones Exacerbates Cerebrovascular and Cognitive Dysfunction in Aortic Banded Miniswine Through a Neuropeptide Y–Ca2+‐Activated Potassium Channel–Nitric Oxide Mediated Mechanism

Loss of Female Sex Hormones Exacerbates Cerebrovascular and Cognitive Dysfunction in Aortic Banded Miniswine Through a Neuropeptide Y–Ca2+‐Activated Potassium Channel–Nitric Oxide Mediated Mechanism

BackgroundPostmenopausal women represent the largest cohort of patients with heart failure with preserved ejection fraction, and vascular dementia represents the most common form of dementia in patients with heart failure with preserved ejection fraction. Therefore, we tested the hypotheses that the...

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Bibliographic Details
Main Authors: T. Dylan Olver, Jessica A. Hiemstra, Jenna C. Edwards, Todd R. Schachtman, Cheryl M. Heesch, Paul J. Fadel, M. Harold Laughlin, Craig A. Emter
Format: Article
Language:English
Published: Wiley 2017-11-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cerebral blood flow
cognition
female sex hormones
heart failure
heart‐brain relationships
vascular biology
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.117.007409

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.117.007409

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