Biphasic effects of statins on neuron cell functions under oxygen–glucose deprivation and normal culturing conditions via different mechanisms

Biphasic effects of statins on neuron cell functions under oxygen–glucose deprivation and normal culturing conditions via different mechanisms

Abstract While there is a growing interest in the use of statins, HMG‐CoA reductase inhibitors, to treat neurodegenerative diseases, statins are associated with conflicting effects within the central nervous system (CNS) without clear evidence of the underlying mechanisms. This study systematically...

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Bibliografiska uppgifter
Huvudupphovsmän: Hui Wang, Yun Chen, Ping Li, Yan Chen, Danfang Yu, Qian Tan, Xiaoli Liu, Zhenli Guo
Materialtyp: Artikel
Språk:English
Publicerad: Wiley 2022-10-01
Serie:Pharmacology Research & Perspectives
Ämnen:
neuron cells
OGD
oxidative stress
prenylation
statins
Länkar:https://doi.org/10.1002/prp2.1001

Internet

https://doi.org/10.1002/prp2.1001

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