Novel Amino Acid Derivatives of Quinolines as Potential Antibacterial and Fluorophore Agents

Novel Amino Acid Derivatives of Quinolines as Potential Antibacterial and Fluorophore Agents

A new series of amino acid derivatives of quinolines was synthesized through the hydrolysis of amino acid methyl esters of quinoline carboxamides with alkali hydroxide. The compounds were purified on silica gel by column chromatography and further characterized by TLC, NMR and ESI-TOF mass spectrome...

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Bibliographic Details
Main Authors: Oussama Moussaoui, Rajendra Bhadane, Riham Sghyar, El Mestafa El Hadrami, Soukaina El Amrani, Abdeslem Ben Tama, Youssef Kandri Rodi, Said Chakroune, Outi M. H. Salo-Ahen
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Scientia Pharmaceutica
Subjects:
alkaline hydrolysis
amino acid derivative
antibacterial activity
DNA gyrase
enzyme inhibitor
fluorescence
Online Access:https://www.mdpi.com/2218-0532/88/4/57

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https://www.mdpi.com/2218-0532/88/4/57

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