A New Multi-Color FISH Assay for Brush Biopsy-Based Detection of Chromosomal Aneuploidy in Oral (Pre)Cancer in Patients with Fanconi Anemia

Background: Fanconi anemia (FA) is a rare inherited DNA instability disorder with a remarkably elevated risk of oral squamous cell carcinoma. These cancers can be detected with oral brush biopsy-based cytology even at early stages. This study aims to determine the diagnostic accuracy of a new multi-...

Full description

Bibliographic Details
Main Authors: Bruno Eduardo Silva de Araujo, Mona Markgraf, Isabela Karoline de Santana Almeida Araujo, Eunike Velleuer, Ralf Dietrich, Natalia Pomjanski, Martin Schramm
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/14/3468