Neuroactive steroid effects on autophagy in a human embryonic kidney 293 (HEK) cell model

Abstract Neuropsychiatric and neurodegenerative disorders are correlated with cellular stress. Macroautophagy (autophagy) may represent an important protective pathway to maintain cellular homeostasis and functionality, as it targets cytoplasmic components to lysosomes for degradation and recycling....

Full description

Bibliographic Details
Main Authors: Sofia V. Salvatore, Ma. Xenia G. Ilagan, Hongjin Shu, Peter M. Lambert, Ann Benz, Mingxing Qian, Douglas F. Covey, Charles F. Zorumski, Steven Mennerick
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-51582-x