Fine-Scale Reconstruction of the Evolution of FII-33 Multidrug Resistance Plasmids Enables High-Resolution Genomic Surveillance

Fine-Scale Reconstruction of the Evolution of FII-33 Multidrug Resistance Plasmids Enables High-Resolution Genomic Surveillance

ABSTRACT We examined 185 complete, publicly available FII-33 plasmid sequences, characterizing their backbone and various insertions. The variable characteristic insertions facilitated evolutionary reconstruction for this plasmid group, beginning with the acquisition of a primary resistance region (...

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Bibliographic Details
Main Authors: Ya Hu, Robert A. Moran, Grace A. Blackwell, Alan McNally, Zhiyong Zong
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:mSystems
Subjects:
Enterobacteriaceae
Klebsiella
antibiotic resistance
carbapenem resistance
plasmid typing
plasmids
Online Access:https://journals.asm.org/doi/10.1128/msystems.00831-21

Internet

https://journals.asm.org/doi/10.1128/msystems.00831-21

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