Suppression of cell-mediated immunity following recognition of phagosome-confined bacteria.

Listeria monocytogenes is a facultative intracellular pathogen capable of inducing a robust cell-mediated immune response to sub-lethal infection. The capacity of L. monocytogenes to escape from the phagosome and enter the host cell cytosol is paramount for the induction of long-lived CD8 T cell-med...

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Bibliographic Details
Main Authors: Keith S Bahjat, Nicole Meyer-Morse, Edward E Lemmens, Jessica A Shugart, Thomas W Dubensky, Dirk G Brockstedt, Daniel A Portnoy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2731223?pdf=render