Genetic insight into the putative causal proteins and druggable targets of osteoporosis: a large-scale proteome-wide mendelian randomization study

Genetic insight into the putative causal proteins and druggable targets of osteoporosis: a large-scale proteome-wide mendelian randomization study

Background: Osteoporosis is a major causative factor of the global burden of disease and disability, characterized by low bone mineral density (BMD) and high risks of fracture. We aimed to identify putative causal proteins and druggable targets of osteoporosis.Methods: This study utilized the larges...

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Bibliographic Details
Main Authors: Zhichong Wu, Kenneth Guangpu Yang, Tsz-Ping Lam, Jack Chun Yiu Cheng, Zezhang Zhu, Wayne Yuk-Wai Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Genetics
Subjects:
mendelian randomization
osteoporosis
BMD
genetic
drug
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1161817/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1161817/full

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