The Effect of Tauroursodeoxycholic Acid (TUDCA) Treatment on Pregnancy Outcomes and Vascular Function in a Rat Model of Advanced Maternal Age

The Effect of Tauroursodeoxycholic Acid (TUDCA) Treatment on Pregnancy Outcomes and Vascular Function in a Rat Model of Advanced Maternal Age

Advanced maternal age (≥35 years) increases the risk of vascular complications in pregnancy that can result in fetal growth restriction and preeclampsia. Endoplasmic reticulum (ER) stress has been linked to adverse pregnancy outcomes in these complicated pregnancies. However, the role of ER stress i...

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Bibliographic Details
Main Authors: Mazhar Pasha, Raven Kirschenman, Amy Wooldridge, Floor Spaans, Christy-Lynn M. Cooke, Sandra T. Davidge
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Antioxidants
Subjects:
advanced maternal age
pregnancy outcomes
endoplasmic reticulum stress
tauroursodeoxycholic acid
wire myography
endothelium-dependent relaxation
Online Access:https://www.mdpi.com/2076-3921/11/7/1275

Internet

https://www.mdpi.com/2076-3921/11/7/1275

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