Bac-EPIC: A web interface for developing novel efflux pump inhibitor compounds targeting Escherichia coli

Multidrug resistance (MDR) poses a severe threat to human health. The existence of efflux pumps primarily contributes to resistance in Gram-negative bacterial infections. Efflux pump inhibitors (EPIs) can potentially improve the efficacy of antibiotics and reduce bacterial pathogenicity by inhibitin...

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Bibliographic Details
Main Authors: Shweta Singh Chauhan, Priyam Pandey, Sabrina Manickam, Ramakrishnan Parthasarathi
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Medicine in Drug Discovery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590098623000143