Design of a synthesis‐friendly hypoxia‐responsive promoter for cell‐based therapeutics

Abstract Towards the goal of making ‘smart’ cell therapies, one that recognizes disease conditions (e.g. hypoxia) and then produces mitigating biologics, it is important to develop suitable promoters. Currently, hypoxia responsive promoters are composed of strongly repeated sequences containing hypo...

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Bibliographic Details
Main Authors: Chee Ka Candice Lam, Kevin Truong
Format: Article
Language:English
Published: Wiley-VCH 2021-12-01
Series:Engineering in Life Sciences
Subjects:
Online Access:https://doi.org/10.1002/elsc.202100045