Role of leucine-rich repeat kinase 2 in severe acute pancreatitis

Role of leucine-rich repeat kinase 2 in severe acute pancreatitis

IntroductionIntrapancreatic activation of trypsinogen caused by alcohol or high-fat intake and the subsequent autodigestion of the pancreas tissues by trypsin are indispensable events in the development of acute pancreatitis. In addition to this trypsin-centered paradigm, recent studies provide evid...

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Bibliographic Details
Main Authors: Yasuo Otsuka, Kosuke Minaga, Masatoshi Kudo, Tomohiro Watanabe
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
leucine-rich repeat kinase 2 (LRRK2)
pancreatitis
fungi
tumor necrosis factor alpha (TNF-α)
interleukin 6 (IL-6)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1364839/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1364839/full

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