Position-specific evolution in transcription factor binding sites, and a fast likelihood calculation for the F81 model

Position-specific evolution in transcription factor binding sites, and a fast likelihood calculation for the F81 model

Transcription factor binding sites (TFBS), like other DNA sequence, evolve via mutation and selection relating to their function. Models of nucleotide evolution describe DNA evolution via single-nucleotide mutation. A stationary vector of such a model is the long-term distribution of nucleotides, un...

Full description

Bibliographic Details
Main Authors: Pavitra Selvakumar, Rahul Siddharthan
Format: Article
Language:English
Published: The Royal Society 2024-01-01
Series:Royal Society Open Science
Subjects:
transcription factor binding site
evolution
compensatory mutation
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.231088

Internet

https://royalsocietypublishing.org/doi/10.1098/rsos.231088

Similar Items