RhoA Is a Crucial Regulator of Myoblast Fusion

RhoA Is a Crucial Regulator of Myoblast Fusion

Satellite cells (SCs) are adult muscle stem cells that are mobilized when muscle homeostasis is perturbed. Here we show that RhoA in SCs is indispensable to have correct muscle regeneration and hypertrophy. In particular, the absence of RhoA in SCs prevents a correct SC fusion both to other RhoA-del...

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Bibliographic Details
Main Authors: Chiara Noviello, Kassandra Kobon, Voahangy Randrianarison-Huetz, Pascal Maire, France Pietri-Rouxel, Sestina Falcone, Athanassia Sotiropoulos
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cells
Subjects:
adult muscle stem cells
muscle regeneration
small GTPase proteins
muscle damage
muscle hypertrophy
muscle cell fusion
Online Access:https://www.mdpi.com/2073-4409/12/23/2673

Internet

https://www.mdpi.com/2073-4409/12/23/2673

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