Developmental Angiogenesis Requires the Mitochondrial Phenylalanyl-tRNA Synthetase

Developmental Angiogenesis Requires the Mitochondrial Phenylalanyl-tRNA Synthetase

Background: Mitochondrial aminoacyl-tRNA synthetases (mtARSs) catalyze the binding of specific amino acids to their cognate tRNAs and play an essential role in the synthesis of proteins encoded by mitochondrial DNA. Defects in mtARSs have been linked to human diseases, but their tissue-specific path...

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Bibliographic Details
Main Authors: Bowen Li, Kun Chen, Fangfang Liu, Juan Zhang, Xihui Chen, Tangdong Chen, Qi Chen, Yan Yao, Weihong Hu, Li Wang, Yuanming Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
mtARSs
FARS2
mitochondrial dysfunction
angiogenesis
zebrafish
HUVECs
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.724846/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2021.724846/full

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