The safety and potential efficacy of exosomes overexpressing CD24 (EXO-CD24) in mild-moderate COVID-19 related ARDS

The safety and potential efficacy of exosomes overexpressing CD24 (EXO-CD24) in mild-moderate COVID-19 related ARDS

Abstract Introduction EXO-CD24 are exosomes genetically manipulated to over-express Cluster of Differentiation (CD) 24. It consists of two breakthrough technologies: CD24, the drug, as a novel immunomodulator that is smarter than steroids without any side effects, and exosomes as the ideal natural d...

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Main Authors: Ioannis Grigoropoulos, Georgios Tsioulos, Artemis Kastrissianakis, Shiran Shapira, Orr Green, Vasiliki Rapti, Maria Tsakona, Thomas Konstantinos, Athina Savva, Dimitra Kavatha, Dimitrios Boumpas, Konstantinos Syrigos, Ioannis Xynogalas, Konstantinos Leontis, Vasileios Ntousopoulos, Vissaria Sakka, Zafeiris Sardelis, Andreas Fotiadis, Lamprini Vlassi, Chrysoula Kontogianni, Anastasia Levounets, Garyfalia Poulakou, Mina Gaga, Ronan MacLoughlin, Justin Stebbing, Nadir Arber, Anastasia Antoniadou, Sotirios Tsiodras
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Respiratory Research
Subjects:
ARDS exosomes
CD24
EXO-CD24
Covid-19
Phase IIb
Online Access:https://doi.org/10.1186/s12931-024-02759-5

Internet

https://doi.org/10.1186/s12931-024-02759-5

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