Discovery of Novel Inhibitors From Medicinal Plants for V-Domain Ig Suppressor of T-Cell Activation

Discovery of Novel Inhibitors From Medicinal Plants for V-Domain Ig Suppressor of T-Cell Activation

V-domain Ig suppressor of T cell activation (VISTA) is an immune checkpoint and is a type I transmembrane protein. VISTA is linked to immunotherapy resistance, and it is a potential immune therapeutic target, especially for triple-negative breast cancer. It expresses at a high concentration in regul...

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Bibliographic Details
Main Authors: Iqra Muneer, Sajjad Ahmad, Anam Naz, Sumra Wajid Abbasi, Adel Alblihy, Abdulaziz A. Aloliqi, Faris F. Aba Alkhayl, Faris Alrumaihi, Sarfraz Ahmad, Youness El Bakri, Muhammad Tahir Ul Qamar
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Molecular Biosciences
Subjects:
VISTA
breast cancer
medicinal plant
phytochemical
MD simulation
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.716735/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.716735/full

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