The response of three-dimensional pancreatic alpha and beta cell co-cultures to oxidative stress

The pancreatic islets of Langerhans have low endogenous antioxidant levels and are thus especially sensitive to oxidative stress, which is known to influence cell survival and behaviour. As bioengineered islets are gaining interest for therapeutic purposes, it is important to understand how their co...

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Bibliographic Details
Main Authors: Mireille M. J. P. E. Sthijns, Timo Rademakers, Jolien Oosterveer, Thomas Geuens, Clemens A. van Blitterswijk, Vanessa L. S. LaPointe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923503/?tool=EBI