Renal Function Mediates the Association Between Klotho and Congestive Heart Failure Among Middle-Aged and Older Individuals

Renal Function Mediates the Association Between Klotho and Congestive Heart Failure Among Middle-Aged and Older Individuals

ObjectiveUsing a newly released National Health and Nutrition Examination Survey (NHANES) data of serum Klotho, this study aimed to explore the relationship between Klotho and specific cardiovascular diseases (CVD), as well as the mediation effect of renal function, among middle-aged and older indiv...

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Bibliographic Details
Main Authors: Xu Zhu, Xinyi Lu, Ting Yin, Qingqing Zhu, Shi Shi, Iokfai Cheang, Xin Yue, Yuan Tang, Shengen Liao, Yanli Zhou, Haifeng Zhang, Xinli Li, Wenming Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Klotho protein
congestive heart failure
cardiovascular disease
mediation analysis
NHANES
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.802287/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.802287/full

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